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AMedication Guidemust be dispensed with:
Bupropion (Wellbutrin, Zyban) requires a Medication Guide due to risks of suicidal thoughts and neuropsychiatric effects.
Medication Guides are FDA-required leaflets given with specific medications that have serious risks.
Examples of Medications Requiring a Medication Guide:
Antidepressants (e.g., SSRIs, SNRIs, bupropion) Suicide risk
NSAIDs GI bleeding risk
Opioids Addiction risk
Fluoroquinolones Tendon rupture risk
Reference:FDA Medication Guide Requirements, ISMP Patient Safety Guidelines.
What is the first thing a pharmacy technician should do when a body area is exposed to a hazardous substance?
When abody area is exposed to a hazardous substance, thefirst actionshould be tothoroughly flush the area with watertoimmediately remove the contaminantand reduce absorption into the skin.
Flush the affected area with water for at least 15 minutes.
Remove contaminated clothing.
Seek medical attention if needed.
Report the incident to the pharmacy manager.
A . Notify the pharmacy manager Incorrect;the immediate priorityis to flush the area.Reporting comes after decontamination.
C . Call environmental services for cleanup Incorrect; personal exposure should be addressed before worrying about cleanup.
D . Go to the emergency department Incorrect; first aid (flushing with water) should beperformed immediatelybefore seeking additional care if necessary.
Proper Emergency Response:Other Answer Choices Explained:Reference:
USP <800> Guidelines for Handling Hazardous Drugs
OSHA (Occupational Safety and Health Administration) Hazardous Substance Exposure Protocols
PTCB PTCE Exam Content Outline (Medication Safety & Hazardous Drug Handling)
Which of the following should be taken on anempty stomach?
Comprehensive and Detailed Step-by-Step Explanation:
Levothyroxine (Synthroid)is athyroid hormone replacementused to treathypothyroidism. It must be takenon an empty stomachbecause food, calcium, and ironinterfere with its absorption.
Administration Guidelines for Levothyroxine:
Take30-60 minutes before breakfastwith afull glass of water.
Avoidcalcium, iron, and antacidsfor4 hoursafter taking it.
Explanation of Answer Choices:A. LevothyroxineCorrect.Absorption is reduced by food, calcium, and iron.B. Amlodipine Incorrect.A calcium channel blocker that can be taken with or without food.C. Cyclobenzaprine Incorrect.A muscle relaxant with no food restrictions.D. Loratadine Incorrect.An antihistamine that does not require fasting.
Reference:
American Thyroid Association (ATA) Levothyroxine Guidelines
FDA Drug Labeling for Synthroid
It would be most appropriate to dispose of which of the following medications as hazardous waste?
Methotrexateis achemotherapy agentand animmunosuppressantused for cancer and autoimmune diseases.
It is classified ashazardous pharmaceutical wasteunderResource Conservation and Recovery Act (RCRA)due to itstoxicity.
It must be disposed of followingEPA guidelines for hazardous waste disposal.
Reference:RCRA hazardous waste disposal regulations;USP <800> guidelines for hazardous drugs.
Handling hazardous substances should be done:
Comprehensive and Detailed Step-by-Step Explanation:
Hazardous drugs (HDs)must be handled withpersonal protective equipment (PPE), including:
Gloves (chemotherapy-rated)
Gown (disposable, impermeable material)
Eye protection (if splashing risk exists)
Respirator (if airborne exposure is possible)
Explanation of Answer Choices:B. Wearing personal protective equipmentCorrect.USP <800> mandatesPPEfor handling hazardous drugs.A. In a chemical safety cabinet Incorrect.Only sterile hazardous drugs require a biological safety cabinet.C. Using disposable gloves washed between each use Incorrect.Disposable gloves should be discarded, not washed.D. In a positive-pressure clean room Incorrect.Hazardous drugs require negative pressure rooms, not positive pressure.
Reference:
USP <800>: Hazardous Drug Handling
NIOSH Guidelines on PPE for Hazardous Drugs
