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True statements regarding transcription include which of the following?
I The enzyme responsible for initiating transcription is RNA polymerase.
II The genetic information contained in the nucleotide sequence of mRNA is translated into a protein structure.
III The information carried in the gene sequence is transferred to RNA.
Five subjects given a single intravenous dose of a drug have the following elimination half-lives: 3, 9, 6, 5 and 4 h (hours). The mean half-life is:
Approximately 50% of dicloxacillin is excreted unchanged in the urine. If the normal dosage schedule for dicloxacillin is 125 mg q6h, a patient with renal function 20% of normal should receive: